副高级
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马天予
博士、长聘副教授

医学物理与工程研究所副所长

邮 箱: maty@tsinghua.edu.cn

  • 教育背景
  • 工作经历
  • 教学工作
  • 研究领域
  • 研究概况
  • 学术成果
  • 学术兼职
  • 奖励与荣誉

2001.09-2004.06 清华大学 工程物理系 博士

1999.09-2001.06 清华大学 工程物理系 硕士

1995.09-1999.06 清华大学 工程物理系 学士


2020.01-  清华大学 工程物理系 长聘副教授

2016.08 -2019.12 清华大学 工程物理系 准聘副教授

2012.01-2016.07 清华大学 工程物理系 副研究员

2006.12 -2008.11 美国纽约州立大学布法罗分校 核医学系 访问学者

2006.09-2011.12 清华大学 工程物理系 助理研究员

2004.09-2006.07 清华大学 工程物理系 博士后


讲授本科生课程《核医学仪器与方法》、讲授研究生课程《核医学影像物理》

指导硕士生4名(毕业),指导博士生10名(3名毕业,7名在读)

学生获奖情况:

朱艺航获2025年度清华大学优秀博士论文

胡一凡获2024年度清华大学优秀博士论文

张德斌获2023年度清华大学优秀博士毕业生

雷林昕获2024年IEEE MIC 会议最佳口头论文奖候选

郑兴春获2024年SNMMI会议最佳论文奖提名

胡一凡获2023年IEEE MIC会议最佳口头论文奖第一名

张德斌获2023年IEEE MIC会议最佳口头论文奖第二名

朱艺航获2022年IEEE MIC会议最佳海报论文奖第三名

王瑞获2022年IEEE MIC会议最佳口头论文奖候选

胡一凡获2021年IEEE NSS会议最佳口头论文奖第一名

汪锦程获2025年本科生综合论文训练校级优秀奖

张雨溪获2024年本科生综合论文训练校级优秀奖

李沛泽获2023年北京市普通高校优秀本科毕业设计(论文)优秀奖和本科生综合论文训练校级优秀奖

雷林昕获2022年本科生综合论文训练校级优秀奖

郑兴春获2021年本科生综合论文训练系级优秀奖

朱艺航获2021年本科生综合论文训练系级优秀奖

胡一凡获2019北京市普通高校优秀本科毕业设计(论文)优秀奖和本科生综合论文训练校级优秀奖

张德斌获2020年本科生综合论文训练校级优秀奖

王瑞获2020年本科生综合论文训练校级优秀奖




主要从事先进核医学影像技术研究、大型核医学分子影像系统(PET、SPECT)研制、医学影像数据处理分析研究。

提出原始创新的“自准直”成像技术,从机理上解决SPECT问世七十多年来性能受限于机械准直器的瓶颈问题。基于“自准直”成像根技术,研发系列用于核医学影像和核安全监控的先进伽马影像产品并推进在医学和工业界的应用。


承担国家原子能机构核技术研发项目、北京市自然基金重点专题、科技部“科技冬奥”专项课题、国家自然基金面上项目、教育部博士点基金项目等国家和省部级科研项目。


[1] Zhang D, Cheng L, Hu Y, Lyu Z, Wang L, Fang W, Yao R, Ma T. Design optimization and simulated performance evaluation of a self-collimated cardiac SPECT with simultaneous high sensitivity and resolution. Medical Physics. 2025, 52(6): 3823-39.

[2] Yu Z, Lyu Z, Fan P, Wu J, Liu Y, Ma T. Sub-Millimeter Pixelated SPECT Detector Using GAGG:Ce and Light Guide With Optical Barrier Slits. IEEE Transactions on Radiation and Plasma Medical Sciences. 2025:1-1.

[3] Zhang H, Zhao B, Fan P, Wang S, Lu W, Yu Y, Wu Z, Ma T, Liu H, Liu Y. Proton Range Verification Realized via a Multi-Slit Prompt Gamma Imaging System. IEEE Transactions on Radiation and Plasma Medical Sciences, 2025: 1-1.

[4] Xiao M, Song J, Lyu Z, Huang X, Zhang Y, Wang L, He Z, Ma T, Li C, Cao H, Zhang Q, Xiang C, Dong J. Regional Liver Function Assessment Using 99mTc-GSA SPECT/CT Scintigraphy in Malignant Perihilar Biliary Tumor Undergoing Major Liver Resection: A Dual-Center Cohort Study. Ann Surg Oncol, 2025.

[5] Liu L, Gong H, Yu Z, Fan P, Lyu Z, Xu T, Han Y, Liu Y, Ma T. Development of a high-resolution and omnidirectional field-of-view neutron imager. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 2024;1061.

[6] Zhu YH, Lyu Z, Lu WZ, Liu YQ, Ma TY. Fast and Accurate Gamma Imaging System Calibration Based on Deep Denoising Networks and Self-Adaptive Data Clustering. SENSORS. 2023;23.

[7] Zhang D, Lyu Z, Liu Y, He ZX, Yao R, Ma T. Characterization and Assessment of Projection Probability Density Function and Enhanced Sampling in Self-Collimation SPECT. IEEE Transactions on Medical Imaging. 2023;42:2787-2801.

[8] Wang R, Zhang D, Hu Y, Lyu Z, Ma T. High-sensitivity cardiac SPECT system design with collimator-less interspaced mosaic-patterned scintillators. Frontiers in Medicine. 2023;10.

[9] Hu YF, Lyu Z, Fan P, Xu TP, Wang S, Liu YQ, Ma TY. A Wide Energy Range and 4 pi-View Gamma Camera with Interspaced Position-Sensitive Scintillator Array and Embedded Heavy Metal Bars. SENSORS. 2023;23.

[10] Wei QY, Lyu ZL, Jiang NM, Deng ZH, Xu TP, Sun LF, Zhang XF, He ZX, Liu YQ, Ma TY. Study of Tc-99m absorption on micro-sized ion exchange resins to achieve high activity for SPECT. Applied Radiation and Isotopes. 2022;186:5.

[11] Omidvari N, Cheng L, Leung EK, Abdelhafez YG, Badawi RD, Ma T, Qi J, Cherry SR. Lutetium background radiation in total-body PET-A simulation study on opportunities and challenges in PET attenuation correction. Frontiers in nuclear medicine (Lausanne, Switzerland). 2022;2.

[12] Lu WZ, Zhang DB, Fan P, Wang S, Wu ZX, Ma TY, Liu YQ. Simulation Study of a 3-D Multislit Prompt Gamma Imaging System for Proton Therapy Monitoring. IEEE TRANSACTIONS ON RADIATION AND PLASMA MEDICAL SCIENCES. 2022;6:355-365.

[13] Hu YF, Fan P, Lyu Z, Huang JW, Wang S, Xia Y, Liu YQ, Ma TY. Design and performance evaluation of a 4 pi-view gamma camera with mosaic-patterned 3D position-sensitive scintillators. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT. 2022;1023.

[14] Wang R, Liu H, Toyonaga T, Shi LY, Wu J, Onofrey JA, Tsai YJ, Naganawa M, Ma TY, Liu YQ, Chen MK, Mecca AP, O'Dell RS, van Dyck CH, Carson RE, Liu C. Generation of synthetic PET images of synaptic density and amyloid from F-18-FDG images using deep learning. MEDICAL PHYSICS. 2021;48:5115-5129.

[15] Ma TY, Wei QY, Lyu Z, Zhang DB, Zhang HY, Wang R, Dong JH, Liu YQ, Yao RT, He ZX. Self-Collimating SPECT With Multi-Layer Interspaced Mosaic Detectors. IEEE Transactions on Medical Imaging. 2021;40:2152-2169.

[16] Zhang HY, Fan P, Wang S, Xia Y, Xu TP, Wei QY, Lu WZ, Wu ZX, Liu YQ, Ma TY. Design and Performance Evaluation of a BGO + SiPM Detector for High-Energy Prompt Gamma Imaging in Proton Therapy Monitoring. IEEE Transactions on Radiation and Plasma Medical Sciences. 2020;4:184-193.

[17] Wei Q, Ma T, Jiang N, Xu T, Lyu Z, Hu Y, Liu Y. A side-by-side LYSO/GAGG phoswich detector aiming for SPECT imaging. Nuclear Instruments Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors Associated Equipment. 2020:163242.

[18] Wei Q, Jiang N, Xu T, Lyu Z, Ma T, Liu Y. A position sensitive scintillation detector using a side-by-side GAGG-F/GAGG-T phoswich block. Journal of Instrumentation. 2020;15.

[19] Cheng L, Ma TY, Zhang XZ, Peng QY, Liu YQ, Qi JY. Maximum likelihood activity and attenuation estimation using both emission and transmission data with application to utilization of Lu-176 background radiation in TOF PET. MEDICAL PHYSICS. 2020;47:1067-1082.

[20] Ye Q, Fan P, Wang R, Lyu Z, Hu A, Wei Q, Xia Y, Yao R, Liu Y, Ma T. A high sensitivity 4π view gamma imager with a monolithic 3D position-sensitive detector. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 2019;937:31-40.

[21] Lu WZ, Onofrey JA, Lu YH, Shi LY, Ma TY, Liu YQ, Liu C. An investigation of quantitative accuracy for deep learning based denoising in oncological PET. Physics in Medicine and Biology. 2019;64.

[22] Ye Q, Wu J, Lu Y, Naganawa M, Gallezot JD, Ma T, Liu Y, Tanoue L, Detterbeck F, Blasberg J, Chen MK, Casey M, Carson RE, Liu C. Improved discrimination between benign and malignant LDCT screening-detected lung nodules with dynamic over static F-18-FDG PET as a function of injected dose. Physics in Medicine and Biology. 2018;63.

[23] Wei Q, Xu T, Dai T, Wang S, Liu Y, Gu Y, Ma T. Development of a compact DOI-TOF detector module for high-performance PET systems. Nuclear Science and Techniques. 2017;28.

[24] Wei Q, Ma T, Xu T, Liu Y, Wang S, Gu Y. Evaluation of signal energy calculation methods for a light-sharing SiPM-based PET detector. Nuclear Instruments & Methods in Physics Research Section a-Accelerators Spectrometers Detectors and Associated Equipment. 2017;848:81-86.

[25] Wei QY, Ma TY, Wang S, Liu YQ, Gu Y, Dai TT. PET/CT alignment calibration with a non-radioactive phantom and the intrinsic Lu-176 radiation of PET detector. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 2016;835:163-168.

[26] Wei QY, Dai TT, Ma TY, Liu YQ, Gu Y. Crystal Identification in Dual-Layer-Offset DOI-PET Detectors Using Stratified Peak Tracking Based on SVD and Mean-Shift Algorithm. IEEE Transactions on Nuclear Science. 2016;63:2502-2508.

[27] Fan P, Ma TY, Wei QY, Yao RT, Liu YQ, Wang S. Choice of crystal surface finishing for a dual-ended readout depth-of-interaction (DOI) detector. Physics in medicine and biology. 2016;61:1041-1056.

[28] Wei Q, Wang S, Ma T, Wu J, Liu H, Xu T, Xia Y, Fan P, Lyu Z, Liu Y. Performance evaluation of a compact PET/SPECT/CT tri-modality system for small animal imaging applications. Nuclear Instruments & Methods in Physics Research Section a-Accelerators Spectrometers Detectors and Associated Equipment. 2015;786:147-154.

[29] Liu H, Chan C, Grobshtein Y, Ma TY, Liu YQ, Wang S, Stacy MR, Sinusas AJ, Liu C. Anatomical-based partial volume correction for low-dose dedicated cardiac SPECT/CT. Physics in Medicine and Biology. 2015;60:6751-6773.

[30] Fan P, Hutton BF, Holstensson M, Ljungberg M, Pretorius PH, Prasad R, Ma TY, Liu YQ, Wang S, Thorn SL, Stacy MR, Sinusas AJ, Liu C. Scatter and crosstalk corrections for Tc-99m/I-123 dual-radionuclide imaging using a CZT SPECT system with pinhole collimators. Medical Physics. 2015;42:6895-6911.

[31] Yu Y H, Xia Y, Chen J, Hong B Y, Liu Y Q, Wang S, Ma T Y. PET image reconstruction with rotationally symmetric polygonal pixel grid based highly compressible system matrix. Nuclear Science and Techniques, 2013, 24(3).

[32] Xia Y, Yao R T, Deng X, Liu Y Q, Wang S, Ma T Y. Assessment of hybrid rotation-translation scan schemes for in vivo animal SPECT imaging. Physics in Medicine and Biology, 2013, 58(4): 965-83.

[33] Xia Y, Ma T Y, Liu Y Q, Sun X S, Wang S, Shao Y P. Imaging performance evaluation in depth-of-interaction PET with a new method of sinogram generation: A Monte Carlo simulation study. NUCLEAR SCIENCE AND TECHNIQUES, 2011, 22(3): 144-50.

[34] Wei Q Y, Wang S, Ma T Y, Ma F, Dai T T, Xu T P, et al. Influence factors of two dimensional position map on photomultiplier detector block designed by quadrant sharing technique. NUCLEAR SCIENCE AND TECHNIQUES, 2011, 22(4): 224-9.

[35] Dai T T, Ma T Y, Liu H, Cui J J, Wei Q Y, Liu Y Q, et al. A high-resolution small animal SPECT system developed at Tsinghua. NUCLEAR SCIENCE AND TECHNIQUES, 2011, 22(6): 344-8.

[36] Yao R T, Ma T Y, Shao Y P. Derivation of System Matrix from Simulation Data for an Animal SPECT With Slit-Slat Collimator. IEEE Transactions on Nuclear Science, 2009, 56(5): 2651-8.

[37] Ma T Y, Yao R T, Shao Y P, Zhou R. A SVD-Based Method to Assess the Uniqueness and Accuracy of SPECT Geometrical Calibration. IEEE Transactions on Medical Imaging, 2009, 28(12): 1929-39.

[38] Yao R T, Ma T Y, Shao Y P. Lutetium oxyorthosilicate (LSO) intrinsic activity correction and minimal detectable target activity study for SPECT imaging with a LSO-based animal PET scanner. Physics in Medicine and Biology, 2008, 53(16): 4399-415.

[39] Shao Y P, Yao R T, Ma T Y. A novel method to calibrate DOI function of a PET detector with a dual-ended-scintillator readout. Medical Physics, 2008, 35(12): 5829-40.

[40] Xu P, Ma T Y, Jin Y J. Entropy-based method to evaluate the data integrity. Nuclear Instruments and Methods in Physics Research Section a-Accelerators Spectrometers Detectors and Associated Equipment, 2006, 569(2): 412-5.



中国核学会核医学分会常务理事

中国医学装备协会核医学装备分委员会委员

北京医学会核医学分会委员

《IEEE Transactions on Medical Imaging》副主编

《Scientific Reports》编委

《核电子学与探测技术》编委

IEEE NSS/MIC 2018分会主席、IEEE NSS/MIC 2021专题召集人/分会主席、IEEE NSS/MIC 2023专题召集人、IEEE NSS/MIC 2025专题召集人、IEEE MIC 2021/2022 技术成就奖评委、IEEE MIC 2024青年科学家奖评委


2024年第50届日内瓦国际发明展金奖(Gold Award)

2023年第49届日内瓦国际发明展杰出创新奖(Outstanding Innovation Award)与金奖(Gold Award)

2024年清华大学优秀博士论文指导教师

2023年北京市优秀毕业设计论文指导教师

2021年清华大学“科技冬奥”先进个人

2019年北京市优秀毕业设计论文指导教师

2018年清华大学大学生研究训练(SRT)计划优秀项目一等奖/优秀指导教师

2016年清华大学“挑战杯”学生课外科技竞赛二等奖/优秀指导教师

2017年清华大学第二届年度教学优秀奖

2016年清华大学第一届年度教学优秀奖

2016年清华大学“挑战杯”学生课外科技竞赛一等奖/二等奖/优秀指导教师

2015年清华大学第六届青年教师教学大赛一等奖

2013年清华大学优秀班主任二等奖


  • 地址:清华大学工程物理系(刘卿楼)
  • 邮编:100084
  • 电话:010-62785727
  • 邮箱:gwbgs@mail.tsinghua.edu.cn
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